Stem Cell Image Library

Stem Cell Image Library SCR thanks the many contributors who have made this stem cell photo library possible. These images may not be reproduced without the permission of their copyright holders, who are listed below each image. Click on any image to enlarge.
	The image shows a colony of differentiating Human Embryonic Stem Cells double-stained with anti-Oct4 antibody ab19857 (green) and Sox17 antibody (red). The nuclei of Oct4-positive undifferentiated hESCs stained bright green. Staining was restricted to the nuclei. Oct4-positive nuclei were Sox17-negative, and vice versa. This antibody can be used as a marker of Oct4-positive undifferentiated Human Embryonic Stem Cells. Photo: Ludovic Vallier, University of Cambridge.
	ICC/IF image of ab19857 stained Mouse Embryonic Stem cells. The cells were PFA fixed (4% PFA, 20 min) and incubated with the antibody (ab19857, 1�g/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor� 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). The large nuclei of the Feeder cells can be seen in the image; ab19857 does not localise to these nuclei. ab19857 can be seen localising to the much smaller nuclei of the Mouse Embryonic Stem cells. Photo: Abcam PLC.
	Representative phase contrast images of H9 hES cells grown on Oct-3/4. Photo: BD Biosciences.
	Representative phase contrast images of H9 hES cells grown on SSEA (Green: hoechst nuclear stain, blue). Immunoflurescent images were acquired on the BD Pathway� Bioimager using a montage feature to capture a larger portion of colonies. Embryoid bodies formed upon plating H9 cells cultured on BD BioCoat� Matrigel� Matrix plates for ES Culture. Photo: BD Biosciences.
	This image is a higher-magnification view of a small colony of human embryonic stem cells. The cells have been stained to make their components more visible. Photo: M. W. Lensch, Children's Hospital, Boston, MA
	Small colony of human embryonic stem cells. The cells have been stained to make their components more visible. Photo: M. W. Lensch, Children's Hospital, Boston, MA
	A selection of immunolabelled ESI hES cell colonies cultured on mitotically inactivated embryonic mouse feeder cells. Photo: ES Cell International.
	A selection of immunolabelled ESI hES cell colonies cultured on mitotically inactivated embryonic mouse feeder cells. Photo: ES Cell International.
	A selection of immunolabelled ESI hES cell colonies cultured on mitotically inactivated embryonic mouse feeder cells. Photo: ES Cell International.
	A selection of immunolabelled ESI hES cell colonies cultured on mitotically inactivated embryonic mouse feeder cells. Photo: ES Cell International.
	A selection of immunolabelled ESI hES cell colonies cultured on mitotically inactivated embryonic mouse feeder cells. Photo: of ES Cell International.
	Clonal conditionally immortalised human neural stem cell line showing that every cell (cell nucleus stained blue) also expresses the neural stem cell filamentous marker, nestin (in green). Note the homogeneity of the cells. Photo: Prof. John Sinden, Ectins project, Euopean Union.
	Human heterogeneous primary fetal brain stem cell preparation showing that a proportion of the cells (cell nucleus stained blue) are stem cells, showing the characteristic filamentous expression of the neural stem cell marker, nestin (in green). Photo: Prof. John Sinden, Ectins project, Euopean Union.
	Similar to TnestinFITC3, nestin marker now stained with red fluorescence dye. Photo: Prof. John Sinden, Ectins project, Euopean Union.
	Mouse embryonic stem cells with stained nuclei - image 2 These mouse embryonic stem cells have been treated with a stain that makes DNA fluoresce, causing nuclei to appear blue. Photo: Exploratorium.
	Mouse embryonic stem cells. Photo: Exploratorium.
	Mouse embryonic stem cells. Photo: Exploratorium.
	Mouse embryonic stem cells with stained nuclei. These mouse embryonic stem cells have been treated with a stain that makes DNA fluoresce, causing nuclei to appear blue. Photo: Exploratorium.
	Undefined. Photo: Exploratorium.
	Mesenchymal precursor cells. Photo: Mesoblast.
	Normal cells transformed into cancerous cells (whose membranes are stained green). The transformed cells retain their sheet-forming capabilities, resembling the tumor cells found in many patients. They also possess enormous potential to create and spread tumors. As many as one in ten is a cancer stem cell. Photo: Massachusetts Institute of Technology.
	Grown in a newly invented culture medium, these normal human breast cells (whose membranes are stained red) form sheets. Photo: Massachusetts Institute of Technology.
	Human embryonic stem cells were coaxed to differentiate into epithelial (skin) cells atop the two spots of biomaterial shown here. Cytokeratin (a marker of epithelial cells) is stained green; cell nuclei are blue. Photo: Massachusetts Institute of Technology.
	Removal of self-renewal factors releases embryonic stem cells to differentiate along the neural lineage under the influence of fibroblast growth factor and notch signals. Photo: Steve Pollard, Wellcome Trust.
	Brain cancer stem cells stained for GFAP (green). Photo: Steve Pollard, Wellcome Trust.
	An embryoid body, a globular cell cluster that the researchers cultured from mouse embryonic stem cells. Photo: Niels Geijsen, Massachusetts General Hospital/National Science Foundation.
	Mouse embryonic stem cells stained with a fluorescent green marker for embryonic germ cells (precursor sex cells). Photo: Niels Geijsen, Massachusetts General Hospital/National Science Foundation.
	A group of developing embryonic stem cells among other cell types. Photo: Oregon Health and Science University.
	Monkey egg cell prior to removal of the nuclear material. Photo: Oregon Health and Science University.
	Neurons derived from stem cells that were once skin cells. Photo: Oregon Health and Science University.
	Skin cells used to develop stem cells. Photo: Oregon Health and Science University.
	Neural stem cells look in culture, with an epithelial cluster below large radial glial-like cells with an extensive network of long branching processes. Photo: Orion Biosolutions.
	Neural stem cells look in culture, with an epithelial cluster below large radial glial-like cells with an extensive network of long branching processes. Once cultures are switched into the commitment base medium, growth factor withdrawal and retinoic acid induced differentiation proceeds. Photo: Orion Biosolutions.
	Oligodendroglial cells from neurospheres. Photo: Orion Biosolutions.
	How neural stem cells look in culture, with an epithelial cluster below large radial glial-like cells with an extensive network of long branching processes. Photo: Orion Biosolutions.
	Unique neuroepithelial stem cells with more Nestin+ cells than neurospheres. Photo: Orion Biosolutions.
	Novel neuro-glial progenitors express both b-tubulin III and GFAP. Photo: Orion Biosolutions.
	Neurons and glia develop after straightforward differentiation. Photo: Orion Biosolutions.
	In the center of this image is a single human embryonic stem cell colony that has been stained to highlight both the individual cells within the colony as well as the surrounding feeder cells. This small embryonic stem cell colony contains approximately 50 to 80 individual cells, each measuring about 10 micrometers (or 0.000010 meters) wide. Photo: Public Broadcasting System.
	An immunofluorescence image of the tip of the Drosophila testis, showing male germline stem cells and their daughters (green) responding to self renewal signals from the stem cell niche. Somatic stem cells, known as cyst progenitor cells, and differentiating cyst cells are labeled in red. Photo: Dr. Monica Boyle, Salk Institute for Biological Studies.
	The cancer stem cells (CSC) are those that costain with the cell surface marker CD44 (green) in combination with a known stem cell-related nuclear protein (red). Note that the CSC population makes up a distinct layer of cells, stained both red and green, within the overall tumor cells. Photo: Stanford University.
	Colony of the human ES cell line HUES 13, stably expressing cyan fluorescent protein (CFP). Photo: Drs. Chad A. Cowan, Jacob P. Zucker, and Douglas A. Melton, Harvard University.
	Oocyte in the process of nuclear transfer. Photo: Dr. Kitai Kim, Children's Hospital, Boston, MA.
	Image of a colony of human embryonic stem cells, stained with anti-TRA-2-39-FITC. Photo: Dr. Nick Strelchenko at the Reproductive Genetics Institute, Chicago, IL.
	Embryonic mouse brain Neurospheres. Photo: Stem Cell Research, ©2005.
	Embryonic mouse brain Neurospheres. Photo: Stem Cell Research, ©2005.
	Embryonic mouse brain Neurospheres. Photo: Stem Cell Research, ©2005.
	Embryonic mouse brain Neurospheres. Photo: Stem Cell Research, ©2005.
	Pluripotent Haematopoietic Stem Cells Produced by Retrodifferentiation. Photo: Tristem Corporation.
	Products of retrodifferentiated pluripotent haematopoietic stem cells. Photo: Tristem Corporation.
	Products of retrodifferentiated pluripotent haematopoietic stem cells. Photo: Tristem Corporation.
	Products of retrodifferentiated pluripotent haematopoietic stem cells. Photo: Tristem Corporation.
	Products of retrodifferentiated pluripotent haematopoietic stem cells. Photo: Tristem Corporation.
	Neurogenesis of retrodifferentiated pluripotent neuronal stem cells derived from adult leucocytes. Photo: Tristem Corporation.
	Neural stem cells shown in green, neurons in red. Photo: University of California - Irvine.
	Neural stem cells shown in green, neurons in red. Photo: University of California - Irvine.
	Brain cancer stem cells stained for vimentin (red). Photo: S. Pollard, Wellcome Trust.
	Embryonic stem (ES) cell colony stained for Oct4 (red), Nanog (green) and counterstained with DAPI (blue). Note that Nanog expressing cells are a subset of Oct4 positive cells. Photo: Jose Silva, Wellcome Trust.
	Colonies of mouse embryonic stem cells. Photo: Sabrina Lin, University of California, Riverside.
	An embryoid body (or aggregate) of stem cells. Photo: Sabrina Lin, University of California, Riverside.
	This image shows human embryonic stem cells differentiated to neuron-like cells. Photo: Rhiannon Nolan and Larry Goldstein 2006, University of California, San Diego.
	In vitro growth of human embryonic stem cells. In this image, the red lines are microtubules of the cytoskeleton. The blue circles are the cell nucleus, with Oct4 shown in green. Oct4 is a stem cell marker because only human embryonic stem cells have this transcription factor, which binds to specific genes and upregulates them. This transcription factor seems to control the genes that are required to keep a stem cell reproducing, rather than differentiating into different kinds of cells. Feeder-free conditions used in the HSCCF ensure that these images show hESCs uncontaminated by mouse material. Photo: Samantha Zeitlin, Ph.D., University of California, San Diego.
	Image of embryoid bodies grown in vitro from HUES cells. This higher-magnification image shows DNA more clearly in blue. Photo: Human Embryonic Stem Cell Core Facility, Samantha Zeitlin, Ph.D., University of California, San Diego.
	Image of embryoid bodies grown in vitro from HUES cells. In this picture, green represents nestin, a cytoskeleton protein that is found mostly in neuronal precursor cells, but not in mature neurons. Red represents lectin that binds to pre-blood vessel tubules. DNA is in blue (but very dim). Photo: Human Embryonic Stem Cell Core Facility, Samantha Zeitlin, Ph.D., University of California, San Diego.
	A pancreatic tumor generated from cancer stem cells. Photo: Comprehensive Cancer Center, University of Michigan.
	A cluster of leukemia-forming cells from a mouse lacking the Pten gene. Blood-forming stem cells and leukemia-initiating cells differ in their dependence on Pten, and this difference can be used to selectively kill the cancerous cells without harming normal stem cells. Photo: Omer Yilmaz, University of Michigan.
	32B bone marrow aspirate. Photo: University of Michigan.
	46L myeloid maturation. Photo: University of Michigan.
	PTEN 41R Liver Leder Sinusoidal. Photo: University of Michigan.
	PTEN E1L2 Leder Spleen. Photo: University of Michigan.
	PTEN EA6L2 Spleen Leder Stain. Photo: University of Michigan.
	No Description. Photo: University of Newcastle, United Kingdom.
	Red blood cell colony derived from human embryonic stem cells by scientists at the University of Wisconsin-Madison. These are the first specialized human cells to be coaxed down a specific developmental pathway and to be reported in the scientific literature. The ability to make human blood in the lab may one day augment human blood supplies for purposes of transfusion and transplantation. Photo: University of Wisconsin.
	Microscopic 5x view of a colony of undifferentiated human embryonic stems cells being studied in developmental biologist James Thomson's research lab. The embryonic stem cell colonies are the rounded, dense masses of cells. The flat, elongated cells in between the embryonic stem cell colonies are fibroblasts that are used as a "feeder layer" on which the embryonic stem cells are grown. Photo: University of Wisconsin.
	Microscopic 10x view of a colony of undifferentiated human embryonic stems cells being studied in developmental biologist James Thomson's research lab. The embryonic stem cell colonies are the rounded, dense masses of cells. The flat, elongated cells in between the embryonic stem cell colonies are fibroblasts that are used as a "feeder layer" on which the embryonic stem cells are grown. Photo: University of Wisconsin.
	Microscopic 20x view of a colony of undifferentiated human embryonic stems cells being studied in developmental biologist James Thomson's research lab. The embryonic stem cell colonies are the rounded, dense masses of cells. The flat, elongated cells in between the embryonic stem cell colonies are fibroblasts that are used as a "feeder layer" on which the embryonic stem cells are grown. Photo: University of Wisconsin.
	This image depicts a colony of human embryonic stem cells grown over a period of 10 months in the absence of mouse feeder cells. The cell nuclei are stained green; the cell surface appears in red. Photo: University of Wisconsin.
	Derived from human embryonic stem cells, precursor neural cells grow in a lab dish and generate mature neurons (red) and glial cells (green). Photo: courtesy Su-Chun Zhang, University of Wisconsin.
	Colour-enhanced scanning electron micrograph of human embryonic stem cell (gold) growing on a layer of supporting cells (fibroblasts). Stem cells are derived from very early embryos and can be either grown to stay in their original state or triggered to form almost any type of human cell. The fibroblasts provide special factors that maintain the stem cells in their original state. The stem cell appears to be grasped by the underlying fibroblast. Stem cell research could lead to cures for many diseases such as Parkinson's disease, Alzheimer's disease and diabetes, where cells are damaged or absent. Photo: Annie Cavanagh and Dave McCarthy, King's College, London.
	Human embryo revealing the inner cell mass. Photo: Wellcome Trust.
	Scientists can now turn skin cells into embryonic stem cells. Photo: Nissim Benvenisty, Hebrew University, Jerusalem, Israel.
	Germline stem cells. Photo: University of Newcastle, United Kingdom.
	Neuronal differentiation of human NS cells following withdrawal of growth factors. Photo: Y. Sun, PLoS Biology, Wellcome Trust.
	Oligodendrocytes generated from mouse neural stem cells. Photo: S. Pollard, Wellcome Trust.
	Stem cells. Photo: Wellcome Trust.
	ES cell colony derived from a mouse embryo using defined culture conditions. Photo: Wellcome Trust.
	Microscopic 20x view of a colony of undifferentiated human embryonic stems cells. Photo: Lauren E. Yaich, University of Pittsburgh, PA.
	Human embryonic stem cells. Photo: Novacell, Inc.
	Embryonic stem cell. Photo: Science Photo Library, British Broadcasting Corporation, United Kingdom.
	Stem cell tumor. Photo: Science.
	Their image shows the micro-architecture of a cluster of human ES-derived endoderm progenitor cells. The image, acquired by scanning electron microscopy (SEM) at 3,500X magnification, reveals cells that are decorated by a mass of plasma membrane projections. Photo: Australian Stem Cell Centre.
	Bone marrow-derived stem cells labelled with dextran-coated iron oxide nanoparticles conjugated with Tat-FITC. Tat is used as a transfection agent and FITC enables histological verification. Photo: Stem Cell Imaging Group.
	Nanoparticle toxicity: Bone marrow-derived stem cells labelled with large iron oxide particles (2.5 �m) stained for Annexin V (apoptotic marker). Cells labelled with small iron oxide nanoparticles (20 nm) do not undergo apoptosis. Photo: Stem Cell Imaging Group.
	The beginning of human stem cell growth - a small human embryonic stem cell colony (highlighted in yellow) grows on a layer of "feeder cells" that provide critical support for its continued development. Photo: Stemagen.
	Three dimensional structures form in the periphery of a human embryonic stem cell colony - with further growth, stem cell colonies can become organized in more complex structures. Photo: Stemagen.
	The interface of a human embryonic stem cell colony and its underlying support cell layer - this image shows the obvious difference between the stem cells and the support "feeder cells" layer. Photo: Stemagen.
	No description. Photo: Stemagen. Back to Top